The development of the cerebral cortex, known as corticogenesis is the process during which the cerebral cortex of the brain is formed as part of the development of the nervous system of mammals inclu
Layers of the cerebral cortex, oriented from most superficial (top of image) to deepest (bottom of image).
Radial glial cell
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Radial glial cells, or radial glial progenitor cells, are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineag
Development of the cerebral cortex
…radial axis, a key signaling molecule in neuronal migration during corticogenesis. The cerebral cortex is divided into layers. Each layer is formed by radial glial cells located in the ventricular zone or subventricular zone, and then migrate to their final destination. Layer I, the molecular layer, is the first cortical…
G-CSF receptor expression clearly delineates cells of radial glia in the embryonic murine brain. From Kirsch et al., 2008.
Slcla3 in Bergmann Glia
Micrograph showing Bergmann gliosis. H&E stain.
Stages of neuronal development in the fetal cerebral cortex from radial glial cells