Didymus the Blind was a Christian theologian in the Church of Alexandria, where he taught for about half a century. He was a student of Origen, and, after the Second Council of Constantinople condemned Origen, Didymus's works were not copied. Many of his writings are lost, but some of his commentaries and essays survive. He was seen as intelligent and a good teacher.

The Catechetical School of Alexandria was a school of Christian theologians and bishops and deacons in Alexandria. The teachers and students of the school were influential in many of the early theological controversies of the Christian church. It was one of the two major centers of the study of biblical exegesis and theology during Late Antiquity, the other being the School of Antioch.