Distortion and overdrive are forms of audio signal processing used to alter the sound of amplified electric musical instruments, usually by increasing their gain, producing a "fuzzy", "growling", or "gritty" tone. Distortion is most commonly used with the electric guitar, but may also be used with other electric instruments such as electric bass, electric piano, synthesizer and Hammond organ. Guitarists playing electric blues originally obtained an overdriven sound by turning up their vacuum tube-powered guitar amplifiers to high volumes, which caused the signal to distort. While overdriven tube amps are still used to obtain overdrive, especially in genres like blues and rockabilly, a number of other ways to produce distortion have been developed since the 1960s, such as distortion effect pedals. The growling tone of a distorted electric guitar is a key part of many genres, including blues and many rock music genres, notably hard rock, punk rock, hardcore punk, acid rock, and heavy metal music, while the use of distorted bass has been essential in a genre of hip hop music and alternative hip hop known as "SoundCloud rap".

An electric guitar is a guitar that requires external amplification in order to be heard at typical performance volumes, unlike a standard acoustic guitar. It uses one or more pickups to convert the vibration of its strings into electrical signals, which ultimately are reproduced as sound by loudspeakers. The sound is sometimes shaped or electronically altered to achieve different timbres or tonal qualities from that of an acoustic guitar via amplifier settings or knobs on the guitar. Often, this is done through the use of effects such as reverb, distortion and "overdrive"; the latter is considered to be a key element of electric blues guitar music and jazz, rock and heavy-metal guitar-playing. Designs also exist combining attributes of the electric and acoustic guitars: the semi-acoustic and acoustic-electric guitars.