The Dodge Custom 880 is an automobile that was marketed by Dodge from 1962 through the end of the 1965 model year. It was positioned as Dodge's product offer in the mid-price full-size market segment and to help fill the void in Chrysler's lineup left by the discontinuation of DeSoto in 1961.

DeSoto was an American automobile marque that was manufactured and marketed by the DeSoto division of Chrysler Corporation from 1928 to the 1961 model year. More than two million passenger cars and trucks bore the DeSoto brand in North American markets during its existence.