Downtown Baltimore is the central business district of the city of Baltimore traditionally bounded by Martin Luther King, Jr. Boulevard to the west, Franklin Street to the north, President Street to the east and the Inner Harbor area to the south.

Interstate 395 (I-395) is an auxiliary Interstate Highway in the US state of Maryland. Known as Cal Ripken Way, the highway runs 1.98 miles (3.19 km) from I-95 north to Howard Street and Camden Street in Downtown Baltimore, where it provides access to the Inner Harbor and the Baltimore Convention Center. The Interstate also serves the Camden Yards Sports Complex, which contains M&T Bank Stadium and Oriole Park at Camden Yards, homes of the Baltimore Ravens and Baltimore Orioles, respectively. I-395 also serves as the southern terminus of Martin Luther King Jr. Boulevard, an urban arterial that provides a western bypass of Downtown Baltimore and connects I-95 with U.S. Route 40 (US 40), US 1, and I-83. The Interstate is maintained by the Maryland Transportation Authority (MDTA) and, like all Interstates, is a part of the National Highway System.