Durotaxis
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In cellular biology, durotaxis is a form of cell migration in which cells are guided by rigidity gradients, which arise from differential structural properties of the extracellular matrix. Most normal
A diagram of the formation of an atherosclerotic plaque. Note the blue vascular smooth muscle cells, which migrate from the tunica media into the tunica intima, where the stiff plaque is forming.
Cell migration
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Cell migration is the movement of cells, either individually or as a group. It is a central process in the development and maintenance of multicellular organisms: tissue formation during embryonic dev
Durotaxis
…In cellular biology, durotaxis is a form of cell migration in which cells are guided by rigidity gradients, which arise from differential structural properties of the extracellular matrix (ECM). Most normal…
(A) Dynamic microtubules are necessary for tail retraction and are distributed at the rear end in a migrating cell. Green, highly dynamic microtubules; yellow, moderately dynamic microtubules and red, stable microtubules. (B) Stable microtubules act as struts and prevent tail retraction and thereby inhibit cell migration.
Schematic representation of the collective biomechanical and molecular mechanism of cell motion
Auklet flock Shumagins 1986
Rearward membrane flow (red arrows) and vesicle trafficking from back to front (blue arrows) drive adhesion-independent migration.