The East–West All-Star Game was an annual all-star game for Negro league baseball players. The game was the brainchild of Gus Greenlee, owner of the Pittsburgh Crawfords. In 1933 he decided to emulate the Major League Baseball All-Star Game, using Negro league players. Newspaper balloting was set up to allow the fans to choose the starting lineups for that first game, a tradition that continued through the series' end in 1962. Unlike the white All-Star game which is played near the middle of the season, the Negro All-Star game was held toward the end of the season.

The Negro leagues were United States professional baseball leagues comprising teams of African Americans. The term may be used broadly to include professional black teams outside the leagues and it may be used narrowly for the seven relatively successful leagues beginning in 1920 that are sometimes termed "Negro Major Leagues".