East End Houston, managed by the East End District (EED), is a district in eastern Houston, Texas, United States, located between the eastern edge of downtown to the Port of Houston and South to Hobby Airport. The District is home to Houston's early history and industry and is the site of Harrisburg, the seat of government for the Republic of Texas in 1836. East End Houston consists of many different ethnic groups, including Hispanic, Asian, White, and African American. Latinos make up more than half of the 100,512 residents, The area includes two of Houston's oldest Hispanic neighborhoods, Magnolia Park and Second Ward.

Downtown is the largest central business district in the city of Houston and the largest in the state of Texas, located near the geographic center of the metropolitan area at the confluence of Interstate 10, Interstate 45, and Interstate 69. The 1.84-square-mile (4.8 km2) district, enclosed by the aforementioned highways, contains the original townsite of Houston at the confluence of Buffalo Bayou and White Oak Bayou, a point known as Allen's Landing. Downtown has been the city's preeminent commercial district since its founding in 1836.