EnCor Biotechnology is an American company that manufactures monoclonal and polyclonal antibodies with a focus on reagents targeting neural proteins. EnCor was founded in 1999 as a spin-off from the U
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Rat brain cells grown in tissue culture and stained, in green, with an EnCor mouse monoclonal antibody to neurofilament subunit NF-L, (HGNC name NEFL), which reveals a large neuron. The cells in the above image were also stained in red with an EnCor rabbit antibody to α-internexin, which in this culture is found in neuronal stem cells.
A formalin fixed and paraffin embedded section of human cerebellum stained with an EnCor mouse monoclonal antibody to NF-L revealed with a brown dye, cell nuclei are revealed with a blue dye. Nuclear rich region at left is the cerebellar granular layer, the region at the right with fewer nuclei is the cerebellar molecular layer. The NF-L antibody binds processes of basket cells, parallel fiber axons, the perikarya of Purkinje and some smaller neurons and various other fine axons.
Internexin, alpha-internexin, is a Class IV intermediate filament approximately 66 kDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neur
EnCor Biotechnology
…subunit NF-L, (HGNC name NEFL), which reveals a large neuron. The cells in the above image were also stained in red with an EnCor rabbit antibody to α-internexin, which in this culture is found in neuronal stem cells. A formalin fixed and paraffin embedded section of human cerebellum stained with an EnCor mouse…
Mixed neuron/glial cultures from p18 rat embryo brain stained with antibody to alpha-internexin which reveals, in red, neuronal processes and cell bodies. Cells were also labelled in green for Coronin 1a, a marker for microglia.