UF Innovate | Accelerate @ Sid Martin Biotech is located in Alachua, Florida, in Progress Park. The program's mission is to foster the growth of bioscience startup companies that have some relationship to the university. The Incubator works with companies in all product areas relating to the life sciences, biomedical research, medicine, and chemical sciences.

Alachua is the second-largest city in Alachua County, Florida and the third-largest in North Central Florida. According to the 2020 census, the city's population was 10,574, up from 9,059 at the 2010 census. It is part of the Gainesville, Florida Metropolitan Statistical Area. Alachua has one of the largest bio and life sciences sectors in Florida and is the site for the Santa Fe College Perry Center for Emerging Technologies.