Endochondral ossification
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Endochondral ossification is one of the two essential pathways by which bone tissue is produced during fetal development and bone repair of the mammalian skeletal system, the other pathway being intra
A schematic representation of endochondral ossification.
A schematic for long bone endochondral ossification.
Light micrograph of undecalcified epiphyseal plate showing endochondral ossification: healthy chondrocytes (top) become degenerating ones (bottom), characteristically displaying a calcified extracellular matrix.
Zones of endochondral ossification.
Epiphyseal plate
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The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone. It is the part of a long bone where new bone growth takes pla
Endochondral ossification
…Articular cartilage: This layer coats the bone ends, concerned with joint movement. Epiphyseal growth plate: This transverse layer lies between the epiphysis and diaphysis. It's composed of highly active chondrocytes and responsible for longitudinal bone…
Radiogram of distal tibia (left) and fibula (right) showing two epiphyseal plates
Masson Goldner trichrome stain of rabbit epiphysial plate