Intramembranous ossification is one of the two essential processes during fetal development of the gnathostome skeletal system by which rudimentary bone tissue is created. Intramembranous ossification
Transmission electron micrograph of a mesenchymal stem cell that is displaying typical ultrastructural characteristics.
Light micrograph of a nidus consisting of osteoprogenitor cells that are displaying a prominent Golgi apparatus.
Light micrograph of a nidus consisting of osteoblasts, many are displaying a prominent Golgi apparatus, that have created osteoid at its center.
Light micrograph of an undecalcified nidus consisting of rudimentary bone tissue that is lined by numerous osteoblasts.
Mesenchymal stem cells, also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts,
Intramembranous ossification
…which is the other process by which bone tissue is created during fetal development, cartilage is not present during intramembranous ossification. Mesenchymal stem cells within mesenchyme or the medullary cavity of a bone fracture initiate the process of intramembranous ossification. A mesenchymal stem cell, or MSC, is…
Human bone marrow-derived Mesenchymal stem cell showing fibroblast-like morphology seen under phase contrast microscope (Carl Zeiss Axiovert 40 CFL) at 63 x magnification
Typical gross appearance of a tubular cartilaginous construct engineered from amniotic mesenchymal stem cells