Enkidu (Sumerian: 𒂗𒆠𒄭 EN.KI.DU10) was a legendary figure in ancient Mesopotamian mythology, wartime comrade and friend of Gilgamesh, king of Uruk. Their exploits were composed in Sumerian poems and in the Akkadian Epic of Gilgamesh, written during the 2nd millennium BC. He is the oldest literary representation of the wild man, a recurrent motif in artistic representations in Mesopotamia and in Ancient Near East literature. The apparition of Enkidu as a primitive man seems to be a potential parallel of the Old Babylonian version (1300–1000 BC), in which he was depicted as a servant-warrior in the Sumerian poems.

Humbaba, originally known as Ḫuwawa in Sumerian, was a figure in Mesopotamian mythology. The origin and meaning of his name are unknown. He was portrayed as an anthropomorphic figure comparable to an ogre or giant. He is best known from Sumerian and Akkadian narratives focused on the hero Gilgamesh, including short compositions belonging to the curriculum of scribal schools, various versions of the Epic of Gilgamesh, and several Hurrian and Hittite adaptations. He is invariably portrayed as the inhabitant or guardian of the cedar forest, to which Gilgamesh ventures with his companion Enkidu. The subsequent encounter leads to the death of Humbaba, which provokes the anger of the gods. Humbaba is also attested in other works of Mesopotamian literature. Multiple depictions of him have also been identified, including combat scenes and apotropaic clay heads.