Erythropoiesis
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Erythropoiesis is the process which produces red blood cells, which is the development from erythropoietic stem cell to mature red blood cell.
Life cycle of a red blood cell
Extramedullary hematopoiesis
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Extramedullary hematopoiesis or extramedullary haematopoiesis refers to hematopoiesis occurring outside of the medulla of the bone. It can be physiologic or pathologic.
Erythropoiesis
…in humans with certain diseases and in some animals, erythropoiesis also occurs outside the bone marrow, within the spleen or liver. This is termed extramedullary erythropoiesis. The bone marrow of essentially all the bones produces red blood cells until a person is around five years old. The tibia and femur cease to be important…
Micrograph showing nucleated red blood cells (bottom left of image), one of the elements necessary to call extramedullary hematopoiesis, in an endometrial polyp. H&E stain.