The Everett McKinley Dirksen United States Courthouse, commonly referred to as the Dirksen Federal Building, is a skyscraper in the Chicago Loop at 219 South Dearborn Street. It was designed by Ludwig Mies van der Rohe and completed in 1964. The building is 384 feet (117 m) tall with 30 floors; it was named for U.S. Congressman Everett Dirksen. The building houses the United States Court of Appeals for the Seventh Circuit, the United States District Court for the Northern District of Illinois, the United States Bankruptcy Court, the United States Marshal for the Northern District of Illinois, United States Attorney for the Northern District of Illinois, and local offices for various court-related federal agencies, such as the Federal Public Defender, United States Probation Service, United States Trustee, and National Labor Relations Board. It is one of three buildings making up the modernist Chicago Federal Center complex designed by van der Rohe, along with Federal Plaza, the U.S. Post Office and the Kluczynski Federal Building. Separate from the Federal Plaza, but opposite the Kluczynski Building across Jackson Boulevard, is the Metcalfe Federal Building.

The Loop, one of Chicago's 77 designated community areas, is the central business district of the city and is the main section of Downtown Chicago. Home to Chicago's commercial core, it is the second largest commercial business district in North America after Midtown Manhattan in New York City, and contains the headquarters and regional offices of several global and national businesses, retail establishments, restaurants, hotels, and theaters, as well as many of Chicago's most famous attractions. It is home to Chicago's City Hall, the seat of Cook County, and numerous offices of other levels of government and consulates of foreign nations. The intersection of State Street and Madison Street is the origin point for the address system on Chicago's street grid. Most of Grant Park's 319 acres are in the eastern section of the community area. The Loop community area is bounded on the north and west by the Chicago River, on the east by Lake Michigan, and on the south by Roosevelt Road.