The Federation of Rhodesia and Nyasaland, also known as the Central African Federation (CAF), was a colonial federation that consisted of three southern African territories: the self-governing British colony of Southern Rhodesia and the British protectorates of Northern Rhodesia and Nyasaland. It existed between 1953 and 1963.

Southern Rhodesia was a landlocked self-governing British Crown colony in southern Africa, established in 1923 and consisting of British South Africa Company (BSAC) territories lying south of the Zambezi River. The region was informally known as south Zambesia until annexed by Britain at the behest of Cecil Rhodes's British South Africa Company, for whom the colony was named. The bounding territories were Bechuanaland (Botswana), Northern Rhodesia (Zambia), Portuguese Mozambique (Mozambique), and the Transvaal Republic.