Florence is a coastal city in Lane County, in the U.S. state of Oregon. It lies at the mouth of the Siuslaw River on the Pacific Ocean and about midway between Newport to the north and Coos Bay to the south along U.S. Route 101. As of August 14, 2023, the city had a total population of 9,553.

Lane County is one of the 36 counties in the U.S. state of Oregon. As of the 2020 census, the population was 382,971, making it the fourth-most populous county in Oregon. The county seat is Eugene, the state's second most populous city. It is named in honor of Joseph Lane, Oregon's first territorial governor.