The Fornax Cluster is a cluster of galaxies lying at a distance of 19 megaparsecs (62 million light-years). It has an estimated mass of (7±2)×1013 solar masses, making it the second richest galaxy cluster within 100 million light-years, after the considerably larger Virgo Cluster. It may be associated with the nearby Eridanus Group. It lies primarily in the constellation Fornax, with its southern boundaries partially crossing into the constellation of Eridanus, and covers an area of sky about 6° across or about 28 sq degrees.

A galaxy cluster, or a cluster of galaxies, is a structure that consists of anywhere from hundreds to thousands of galaxies that are bound together by gravity, with typical masses ranging from 1014 to 1015 solar masses. They are the second-largest known gravitationally bound structures in the universe after some superclusters (of which only one, the Shapley Supercluster, is known to be bound). They were believed to be the largest known structures in the universe until the 1980s, when superclusters were discovered. One of the key features of clusters is the intracluster medium (ICM). The ICM consists of heated gas between the galaxies and has a peak temperature between 2–15 keV that is dependent on the total mass of the cluster. Galaxy clusters should not be confused with galactic clusters (also known as open clusters), which are star clusters within galaxies, or with globular clusters, which typically orbit galaxies. Small aggregates of galaxies are referred to as galaxy groups rather than clusters of galaxies. The galaxy groups and clusters can themselves cluster together to form superclusters.