The Fortaleza de San Fernando is a colonial-era Spanish fortress in Omoa, Honduras. Built between 1756 and 1775, the fortress guarded Spanish interests in the-then Captaincy General of Guatemala before being seized by the Honduran government in 1821. The fortress remains relatively intact, and is a major tourist attraction in Omoa.

Omoa is a town and municipality with a population of 10,550 in the Department of Cortés in Honduras. Omoa is located on a small bay of the same name 18 km west of Puerto Cortés on the Caribbean Sea coast.