The four sons of Horus were a group of four deities in ancient Egyptian religion who were believed to protect deceased people in the afterlife. Beginning in the First Intermediate Period of Egyptian history, Imsety, Hapy, Duamutef, and Qebehsenuef were especially connected with the four canopic jars that housed the internal organs that were removed from the body of the deceased during the process of mummification. Most commonly, Imsety protected the liver, Hapy the lungs, Duamutef the stomach, and Qebehsenuef the intestines, but this pattern often varied. The canopic jars were given lids that represented the heads of the sons of Horus. Although they were originally portrayed as humans, in the latter part of the New Kingdom, they took on their most distinctive iconography, in which Imsety is portrayed as a human, Hapy as a baboon, Duamutef as a jackal, and Qebehsenuef as a falcon. The four sons were also linked with stars in the sky, with regions of Egypt, and with the cardinal directions.

Horus, also known as Heru, Har, Her, or Hor in Ancient Egyptian, is one of the most significant ancient Egyptian deities who served many functions, most notably as the god of kingship, healing, protection, the sun, and the sky. He was worshipped from at least the late prehistoric Egypt until the Ptolemaic Kingdom and Roman Egypt. Different forms of Horus are recorded in history, and these are treated as distinct gods by Egyptologists. These various forms may be different manifestations of the same multi-layered deity in which certain attributes or syncretic relationships are emphasized, not necessarily in opposition but complementary to one another, consistent with how the Ancient Egyptians viewed the multiple facets of reality. He was most often depicted as a falcon, most likely a lanner falcon or peregrine falcon, or as a man with a falcon head.