Franklinton is a neighborhood in Columbus, Ohio, just west of its downtown. Settled in 1797, Franklinton is the first American settlement in Franklin County, and was the county seat until 1824. As the city of Columbus grew, the city annexed and incorporated the existing settlement in 1859. Franklinton is bordered by the Scioto River on the north and east, Harmon Avenue on the east, Stimmel Road and Greenlawn Avenue on the south, and Interstate 70 on the west. Its main thoroughfare is West Broad Street, one of the city's two main roads.

Columbus, the state capital and Ohio's largest city, has numerous neighborhoods within its city limits. Neighborhood names and boundaries are not officially defined. They may vary or change from time to time due to demographic and economic variables.