Frederick V Louis William Christian, Landgrave of Hesse-Homburg was from 1751 to his death landgrave of Hesse-Homburg.

Hesse-Homburg was a state of the Holy Roman Empire and a sovereign member of the German Confederation. It was formed into a separate landgraviate in 1622 by the landgrave of Hesse-Darmstadt; it was to be ruled by his son, although it did not become independent of Hesse-Darmstadt until 1668. It was briefly divided into Hesse-Homburg and Hesse-Homburg-Bingenheim; but these parts were reunited in 1681.