The Fuller Building is a skyscraper at 57th Street and Madison Avenue in the Midtown Manhattan neighborhood of New York City. Designed by Walker & Gillette, it was erected between 1928 and 1929. The building is named for its original main occupant, the Fuller Construction Company, which moved from the Flatiron Building.

57th Street is a broad thoroughfare in the New York City borough of Manhattan, one of the major two-way, east-west streets in the borough's grid. As with Manhattan's other "crosstown" streets, it is divided into its east and west sections at Fifth Avenue. The street runs from a small park overlooking the East River in the east to the West Side Highway along the Hudson River in the west. 57th Street runs through the neighborhoods of Sutton Place, Midtown Manhattan, and Hell's Kitchen from east to west.