General anaesthetics are often defined as compounds that induce a loss of consciousness in humans or loss of righting reflex in animals. Clinical definitions are also extended to include an induced co
General anesthetics are frequently administered as volatile liquids or gases.
In pharmacology, GABAA receptor positive allosteric modulators, also known as GABAkines or GABAA receptor potentiators, are positive allosteric modulator molecules that increase the activity of the GA
Binding sites of different therapeutic chemical groups on a GABAA receptor
GABAergic synapse. The synaptic anchoring protein Gephyrin is indirectly linked to the GABAA receptors.
Synthesis and discovery of chlordiazepoxide
Different R-group analogs for neurosteroids. Groups 1–4 and 10 have significant therapeutic value.