George Edward Lowe is an American voice actor and comedian whose voice roles include Space Ghost on the animated series Space Ghost Coast to Coast and its spin-off, Cartoon Planet. He continued to voice Space Ghost in several cameos in other programs for several years following the conclusion of the series.

Space Ghost Coast to Coast is an American adult animation created by Mike Lazzo for Cartoon Network and first broadcast in 1994. It takes the form of a surreal parody of talk shows, hosted by a reimagined version of the 1960s Hanna-Barbera cartoon character Space Ghost. It incorporates surrealism and non-sequitur humor.