The George Washington was a named passenger train of the Chesapeake and Ohio Railway running between Cincinnati, Ohio and Washington, D.C. that operated from 1932, the 200th anniversary of the birth of George Washington, to 1974. A section divided from the main train at Gordonsville, Virginia and operated through Richmond to Phoebus, Virginia. From the west, a section originated in Louisville and joined at Ashland.

The National Limited was the premier train of the Baltimore and Ohio Railroad (B&O) on its route between Jersey City, New Jersey and St. Louis, Missouri, with major station stops in Washington, D.C., and Cincinnati, Ohio. It operated from 1925 to 1971. For much of its life it offered exclusive all-Pullman service, and it was the first long-distance train to be entirely air-conditioned. The National Limited was one of many trains discontinued when Amtrak began operations on May 1, 1971. Amtrak revived the name for another New York–St. Louis service which did not use the B&O route.