State Route 37 (SR 37) is a 153.6-mile-long (247.2 km) state highway that travels west-to-east through portions of Clay, Calhoun, Baker, Mitchell, Colquitt, Cook, Berrien, Lanier, and Clinch counties in the southwestern and south-central parts of the U.S. state of Georgia. The highway connects the Alabama state line west of Fort Gaines to the Homerville area, via Newton, Camilla, Moultrie, Adel, and Lakeland. The highway actually serves as the eastern terminus of a long multi-state route that starts in Mississippi and goes through Alabama.

Clay County is a county located in the southwestern part of the U.S. state of Georgia. As of the 2020 census, the population was 2,848, making it the fourth-least populous county in Georgia. The county seat is Fort Gaines.