The Georgia Tech–Vanderbilt football rivalry is an American college football rivalry between the Georgia Tech Yellow Jackets and Vanderbilt Commodores. Both universities are founding members of the Southeastern Conference (SEC) and Southern Conference (SoCon), and Southern Intercollegiate Athletic Association (SIAA). Georgia Tech leads the series all time 20–15–3.

The Vanderbilt Commodores football program represents Vanderbilt University in the sport of American football. The Commodores compete in the Football Bowl Subdivision (FBS) of the National Collegiate Athletic Association (NCAA) and the East Division of the Southeastern Conference (SEC). They are led by head coach Clark Lea. Vanderbilt plays their home games at FirstBank Stadium, located on the university's Nashville, Tennessee campus.