A ghetto is a part of a city in which members of a minority group are concentrated, especially as a result of political, social, legal, religious, environmental or economic pressure. Ghettos are often known for being more impoverished than other areas of the city. Versions of such restricted areas have been found across the world, each with their own names, classifications, and groupings of people.

The Venetian Ghetto was the area of Venice in which Jews were forced to live by the government of the Venetian Republic. The English word ghetto is derived from the Jewish ghetto in Venice. The Venetian Ghetto was instituted on 29 March 1516 by decree of Doge Leonardo Loredan and the Venetian Senate. It was not the first time that Jews in Venice were compelled to live in a segregated area of the city. In 1555, Venice had 160,208 inhabitants, including 923 Jews, who were mainly merchants.