Gholam Reza Aghazadeh is an Iranian politician. Aghazadeh served as the Vice President for Atomic Energy of the Islamic Republic of Iran and the president of the Atomic Energy Organization of Iran from September 1997 until his resignation in July 2009. He is currently member of the Expediency Discernment Council.

The Expediency Discernment Council of the System is an administrative assembly of Iran appointed by the Supreme Leader and was created upon the revision to the Constitution on 6 February 1988. It was originally set up to resolve differences or conflicts between the Majlis and the Guardian Council, but "its true power lies more in its advisory role to the Supreme Leader." According to Hooman Majd, the Leader "delegated some of his own authority to the council—granting it supervisory powers over all branches of the government" following President Mahmoud Ahmadinejad's election in 2005.