Gilberto Agustoni was a Swiss prelate of the Catholic Church. He worked in the Roman Curia from 1950 to 1998, ending his career as head of the Apostolic Signatura from 1992 to 1998. He became a Cardinal in 1994.

The Supreme Tribunal of the Apostolic Signatura is the highest judicial authority in the Catholic Church. In addition, it oversees the administration of justice in the church.