Giovanni Pico dei conti della Mirandola e della Concordia, known as Pico della Mirandola, was an Italian Renaissance nobleman and philosopher. He is famed for the events of 1486, when, at the age of 23, he proposed to defend 900 theses on religion, philosophy, natural philosophy, and magic against all comers, for which he wrote the Oration on the Dignity of Man, which has been called the "Manifesto of the Renaissance", and a key text of Renaissance humanism and of what has been called the "Hermetic Reformation". He was the founder of the tradition of Christian Kabbalah, a key tenet of early modern Western esotericism. The 900 Theses was the first printed book to be universally banned by the Church. Pico is sometimes seen as a proto-Protestant, because his 900 theses anticipated many Protestant views.

Agnolo Ambrogini, commonly known as Angelo Poliziano or simply Poliziano, anglicized as Politian, was an Italian classical scholar and poet of the Florentine Renaissance. His scholarship was instrumental in the divergence of Renaissance Latin from medieval norms and for developments in philology. His nickname Poliziano, by which he is chiefly identified to the present day, was derived from the Latin name of his birthplace, Montepulciano.