Giuseppe Cocconi (1914–2008) was an Italian physicist who was director of the Proton Synchrotron at CERN in Geneva. He is known for his work in particle physics and for his involvement with SETI where he wrote, "[t]he probability of success is difficult to estimate; but if we never search, the chance of success is zero."

The hydrogen line, 21 centimeter line, or H I line is a spectral line that is created by a change in the energy state of solitary, electrically neutral hydrogen atoms. It is produced by a spin-flip transition, which means the direction of the electron's spin is reversed relative to the spin of the proton. This is a quantum state change between the two hyperfine levels of the hydrogen 1 s ground state. The electromagnetic radiation producing this line has a frequency of 1420.405751768(2) MHz (1.42 GHz), which is equivalent to a wavelength of 21.106114054160(30) cm in a vacuum. According to the Planck–Einstein relation E = hν, the photon emitted by this transition has an energy of 5.8743261841116(81) μeV [9.411708152678(13)×10−25 J]. The constant of proportionality, h, is known as the Planck constant.