Grand vizier was the title of the effective head of government of many sovereign states in the Islamic world. It was first held by officials in the later Abbasid Caliphate. It was then held in the Ottoman Empire, the Mughal Empire, the Sokoto Caliphate, the Safavid Empire and Cherifian Empire of Morocco. In the Ottoman Empire, the grand vizier held the imperial seal and could convene all other viziers to attend to affairs of the state; the viziers in conference were called "Kubbealtı viziers" in reference to their meeting place, the Kubbealtı in Topkapı Palace. His offices were located at the Sublime Porte. Today, the Prime Minister of Pakistan is referred to in Urdu as Wazir-e-azam, which translates literally to grand vizier.

The Prime Minister of Pakistan is the head of government of the Islamic Republic of Pakistan. Executive authority is vested in the prime minister and his chosen cabinet, despite the president of Pakistan serving as the nominal head of executive. The prime minister is often the leader of the party or the coalition with a majority in the lower house of the Parliament of Pakistan, the National Assembly where he serves as Leader of the House. Prime minister holds office by virtue of their ability to command the confidence of the National Assembly. The prime minister is designated as the "Chief Executive of the Islamic Republic".