The Great Lakes Science Center is a museum and educational facility in downtown Cleveland, Ohio, United States. Many of the exhibits document the features of the natural environment in the Great Lakes region of the United States. The facility includes signature (permanent) and traveling exhibits, meeting space, a cafe, and an IMAX Dome theater.

Downtown Cleveland is the central business district of Cleveland, Ohio, United States. The economic and cultural center of the city and the Cleveland metropolitan area, it is Cleveland's oldest district, with its Public Square laid out by city founder General Moses Cleaveland in 1796.