Greenville is the county seat and most populous city of Pitt County, North Carolina, United States. It is the principal city of the Greenville, NC Metropolitan Statistical Area, and the 12th-most populous city in North Carolina. Greenville is the health, entertainment, and educational hub of North Carolina's Tidewater and Coastal Plain. As of the 2020 census, there were 87,521 people in the city. The city has continued to see a population increase with a majority of the influx being seen during the 20th and early 21st centuries.

Pitt County is a county located in the Inner Banks region of the U.S. state of North Carolina. As of the 2020 census, the population was 170,243, making it the 14th-most populous county in North Carolina. Its county seat is Greenville.