The Guayupe are an Arawak-speaking indigenous group of people in modern-day Colombia. They inhabit the westernmost parts of the department of Meta. At the time of the Spanish conquest, more than 250,000 Guayupe were living in large parts of Meta.

The Guahibo people are an indigenous people native to the Llanos or savanna plains in eastern Colombia and in southern Venezuela near the Colombian border. Their population was estimated at 23,772 people in 1998.