The Guggenheim Aeronautical Laboratory at the California Institute of Technology (GALCIT), was a research institute created in 1926, at first specializing in aeronautics research. In 1930, Hungarian scientist Theodore von Kármán accepted the directorship of the lab and emigrated to the United States. Under his leadership, work on rockets began there in 1936. GALCIT was the first—and from 1936 to 1940 the only—university-based rocket research center. Based on GALCIT's JATO project at the time, the Jet Propulsion Laboratory was established under a contract with the United States Army in November 1943.

Theodore von Kármán, was a Hungarian-American mathematician, aerospace engineer, and physicist who worked in aeronautics and astronautics. He was responsible for crucial advances in aerodynamics characterizing supersonic and hypersonic airflow. The human-defined threshold of outer space is named the "Kármán line" in recognition of his work. Kármán is regarded as an outstanding aerodynamic theoretician of the 20th century.