Guido Reybrouck is a Belgian former road bicycle racer. He is an older brother of Wilfried Reybrouck and the cousin of Gustave Danneels.

The 1965 Tour de France was the 52nd edition of the Tour de France, one of cycling's Grand Tours. It took place between 22 June and 14 July, with 22 stages covering a distance of 4,188 km (2,602 mi). In his first year as a professional, Felice Gimondi, a substitute replacement on the Salvarani team, captured the overall title ahead of Raymond Poulidor, the previous year's second-place finisher.