The Gutenberg Bible, also known as the 42-line Bible, the Mazarin Bible or the B42, was the earliest major book printed in Europe using mass-produced metal movable type. It marked the start of the "Gutenberg Revolution" and the age of printed books in the West. The book is valued and revered for its high aesthetic and artistic qualities and its historical significance.

Printing is a process for mass reproducing text and images using a master form or template. The earliest non-paper products involving printing include cylinder seals and objects such as the Cyrus Cylinder and the Cylinders of Nabonidus. The earliest known form of printing evolved from ink rubbings made on paper or cloth from texts on stone tablets, used during the sixth century. Printing by pressing an inked image onto paper appeared later that century. Later developments in printing technology include the movable type invented by Bi Sheng around 1040 AD and the printing press invented by Johannes Gutenberg in the 15th century. The technology of printing played a key role in the development of the Renaissance and the Scientific Revolution and laid the material basis for the modern knowledge-based economy and the spread of learning to the masses.