H&E stain
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Hematoxylin and eosin stain is one of the principal tissue stains used in histology. It is the most widely used stain in medical diagnosis and is often the gold standard. For example, when a pathologi
Retina (part of the eye) stained with hematoxylin and eosin, cell nuclei stained blue-purple and extracellular material stained pink
Rack of slides being removed from a bath of hematoxylin stain
Ductal carcinoma in situ (DCIS) in breast tissue, cell nuclei (blue-purple), extracellular material (pink)
Lung tissue taken from an emphysema patient. Cell nuclei (blue-purple), red blood cells (bright red), other cell bodies and extracellular material (pink), and air spaces (white).
Staining
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Staining is a technique used to enhance contrast in samples, generally at the microscopic level. Stains and dyes are frequently used in histology, in cytology, and in the medical fields of histopathol
H&E stain
…and eosin stain (or haematoxylin and eosin stain or hematoxylin–eosin stain; often abbreviated as H&E stain or HE stain) is one of the principal tissue stains used in histology. It is the most widely used stain in medical diagnosis and is often the gold standard. For example, when a pathologist looks at a…
A stained histological specimen, sandwiched between a glass microscope slide.
Example of negative staining
PAS diastase showing the fungus Histoplasma.