Helios Airways Flight 522 was a scheduled passenger flight from Larnaca, Cyprus, to Prague, Czech Republic, with a stopover in Athens, Greece. Shortly after take-off on 14 August 2005, air traffic control (ATC) lost contact with the aircraft operating the flight, named Olympia; it eventually crashed near Grammatiko, Greece, killing all 121 passengers and crew on board. It is the deadliest aviation accident in Greek history.

Flight 7500 is a 2014 American supernatural horror film directed by Takashi Shimizu and starring Leslie Bibb, Jerry Ferrara, Ryan Kwanten, and Amy Smart. It revolves around a supernatural force on a plane. The film is loosely based on the Helios Airways Flight 522 incident that took place in 2005. The film was released in the United States on April 12, 2016, by CBS Films and Lionsgate, after being released theatrically in Asia.