Henry, Duke of Cornwall was the first living child of King Henry VIII of England and his first wife, Catherine of Aragon, and though his birth was celebrated as that of the heir apparent, he died within weeks. His death and the failure of Henry VIII and Catherine to produce another surviving male heir led to succession and marriage crises that affected the relationship between the English church and Roman Catholicism, giving rise to the English Reformation.

Henry VIII was King of England from 22 April 1509 until his death in 1547. Henry is known for his six marriages and his efforts to have his first marriage annulled. His disagreement with Pope Clement VII about such an annulment led Henry to initiate the English Reformation, separating the Church of England from papal authority. He appointed himself Supreme Head of the Church of England and dissolved convents and monasteries, for which he was excommunicated by the pope.