Hermann Staudinger was a German organic chemist who demonstrated the existence of macromolecules, which he characterized as polymers. For this work he received the 1953 Nobel Prize in Chemistry.
Hermann Staudinger
Figure 3. A chain of paper clips (above) is a good model for a polymer such as polylactic acid (below). The polymer chain is composed of small pieces linked together in a head-to-tail fashion.
A macromolecule is a very large molecule important to biological processes, such as a protein or nucleic acid. It is composed of thousands of covalently bonded atoms. Many macromolecules are polymers of smaller molecules called monomers. The most common macromolecules in biochemistry are biopolymers and large non-polymeric molecules such as lipids, nanogels and macrocycles. Synthetic fibers and experimental materials such as carbon nanotubes are also examples of macromolecules.
Chemical structure of a polypeptide macromolecule
Structure of an example polyphenylene dendrimer macromolecule.