Salesforce Tower, 110 Bishopsgate is a commercial skyscraper in London. It stands 230 metres (755 ft) tall including its 28-metre (92 ft) mast making it the second tallest building in the City of London financial district and the fifth tallest in Greater London and the United Kingdom, after the Shard in Southwark and One Canada Square at Canary Wharf. 110 Bishopsgate is located on Bishopsgate and is bordered by Camomile Street, Outwich Street and Houndsditch.

The City of London, widely referred to simply as the City, is a city, ceremonial county and local government district that contains the ancient centre, and constitutes, along with Canary Wharf, the primary central business district (CBD) of London and one of the leading financial centres of the world. It constituted most of London from its settlement by the Romans in the 1st century AD to the Middle Ages, but the modern area referred to as London has since grown far beyond the City of London boundary. The City is now only a small part of the metropolis of Greater London, though it remains a notable part of central London. The City of London is not one of the London boroughs, a status reserved for the other 32 districts. It is also a separate ceremonial county, being an enclave surrounded by Greater London, and is the smallest ceremonial county in England.