Hill equation (biochemistry)
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In biochemistry and pharmacology, the Hill equation refers to two closely related equations that reflect the binding of ligands to macromolecules, as a function of the ligand concentration. A ligand i
A trio of dose response curves
Langmuir adsorption model
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The Langmuir adsorption model explains adsorption by assuming an adsorbate behaves as an ideal gas at isothermal conditions. According to the model, adsorption and desorption are reversible processes.
Hill equation (biochemistry)
…equation reflects the occupancy of macromolecules: the fraction that is saturated or bound by the ligand. This equation is formally equivalent to the Langmuir isotherm. Conversely, the Hill equation proper reflects the cellular or tissue response to the ligand: the physiological output of the system, such as muscle…
A schematic showing equivalent sites, occupied (blue) and unoccupied (red), clarifying the basic assumptions used in the model. The adsorption sites (heavy dots) are equivalent and can have unit occupancy. Also, the adsorbates are immobile on the surface.