Hopkins County is a county located in the western part of the U.S. state of Kentucky. As of the 2020 census, the population was 45,423. Its county seat is Madisonville. Hopkins County was created December 9, 1806, from Henderson County. It was named for General Samuel Hopkins, an officer in both the American Revolutionary War and War of 1812, and later a Kentucky legislator and U.S. Congressman.

Webster County is a county located in the U.S. state of Kentucky. As of the 2020 census, the population was 13,017. Its county seat is Dixon and its largest city is Providence. It is the southernmost county in the Evansville, IN–KY Metropolitan Statistical Area. The county was formed in 1860 from parts of Henderson, Hopkins, and Union Counties and named for American statesman Daniel Webster (1782–1852). It was mainly pro-Confederate during the American Civil War and was the site of several skirmishes and some guerrilla warfare. Since 2018 it has been a moist county, with Providence and Sebree voting to allow alcohol sales, and Clay doing so in 2022.