Houston Hall is the student union of the University of Pennsylvania, in Philadelphia, Pennsylvania. Completed in 1896, it was the first student union built on an American college campus.

Henry H. Houston was a leading Philadelphia businessman and philanthropist. He worked in iron and transportation industries and invested in oil and precious metal concerns. He sat on boards of a number of railroad organizations and he was trustee of the University of Pennsylvania and Washington and Lee University. He developed Wissahickon Heights, an exclusive community in western Chestnut Hill.