Houston Street is a major east–west thoroughfare in Lower Manhattan in New York City, United States. It runs the full width of the island of Manhattan, from FDR Drive along the East River in the east to the West Side Highway along the Hudson River in the west. The street is divided into west and east sections by Broadway.

Franklin D. Roosevelt East River Drive, commonly called FDR Drive for short, is a controlled-access parkway on the east side of the New York City borough of Manhattan. It starts near South and Broad Streets, just north of the Battery Park Underpass, and runs north along the East River to the 125th Street / Robert F. Kennedy Bridge interchange, where it becomes Harlem River Drive. All of FDR Drive is designated New York State Route 907L (NY 907L), an unsigned reference route.