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TSC SNP distribution along the long arm of chromosome 22 (from https://web.archive.org/web/20130903043223/http://snp.cshl.org/ ). Each column represen
TSC SNP distribution along the long arm of chromosome 22 (from https://web.archive.org/web/20130903043223/http://snp.cshl.org/ ). Each column represents a 1 Mb interval; the approximate cytogenetic position is given on the x-axis. Clear peaks and troughs of SNP density can be seen, possibly reflecting different rates of mutation, recombination and selection.
Populations with a high level of parental-relatedness result in a larger number of homozygous gene knockouts as compared to outbred populations.
Populations with a high level of parental-relatedness result in a larger number of homozygous gene knockouts as compared to outbred populations.
A pedigree displaying a first-cousin mating (carriers both carrying heterozygous knockouts mating as marked by double line) leading to offspring posse
A pedigree displaying a first-cousin mating (carriers both carrying heterozygous knockouts mating as marked by double line) leading to offspring possessing a homozygous gene knockout
Logo of the Human Genome Project
Logo of the Human Genome Project
Wellcome
Wellcome